Binding domain mapping and compounds, compositions, complexes, methods, and kits related thereto
AssigneeGeorge Mason Research Foundation, Inc.
InventorsLance Liotta, Alessandra Luchini Kunkel, Amanda Still, Mikell Paige
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Abstract
The present disclosure relates to compounds, complexes, compositions, kits and methods for determining interacting and/or binding sites between e.g., proteins, proteins and nucleic acids, proteins and small molecules, or intrachain protein domains. The disclosure provides rapid and direct positive identification of the contact interface region between such molecules, and can be applied to individual interacting pairs, as well as large-scale or global interactions.
Claims5
A peptide comprising the amino acid sequence set forth as:
- CYRAMISYGGADYKRITC (SEQ ID NO:2);
- CLKYDAPAFTVTC (SEQ ID NO:4);
- or
- CLNWYRMSPSNQTDKLAAC (SEQ ID NO:7).
A peptide comprising the amino acid sequence set forth as:
- CYRAMISYGGADYKRITC (SEQ ID NO:2).
A peptide comprising the amino acid sequence set forth as:
- CLKYDAPAFTVTC (SEQ ID NO:4).
A peptide comprising the amino acid sequence set forth as:
- CLNWYRMSPSNQTDKLAAC (SEQ ID NO:
- 7).
Dependencies are inferred from the claim text.