LSD derivatives, synthesis and method for treatment of diseases and disorders
AssigneeBetterlife Pharma Inc.
InventorsHooshmand Sheshbaradaran, Scott Rudge, Abdi Ghaffari, Stefan Soderman, Petar Duspara
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Abstract
LSD derivative compounds and polymorphs thereof, methods for their synthesis, compositions and treatment of diseases and disorders are described herein, the compounds having the structure of Formula I: including pharmaceutically acceptable salts, hydrates, solvates, tautomers, enantiomers, diastereomers, racemates, polymorphs or combinations thereof; wherein: R1 to R14 are each independently selected from H, or a substituted or unsubstituted hydrocarbon group and X is selected from a halo group.
Claims19
A substantially pure crystalline form of a compound selected from:
- wherein the compound has a Powder X-ray Diffraction (PXRD) pattern comprising a peak at 10.3°±0.2° (2θ).
A substantially pure crystalline form of a compound selected from:
- wherein the compound has a Powder X-ray Diffraction (PXRD) pattern comprising a peak at 10.3°±0.2° (2θ) and another peak at one or more of 4.7°±0.2° (2θ), 9.4°±0.2° (2θ), and 20.1°±0.2° (2θ).
A substantially pure crystalline form of a compound selected from:
- wherein the compound has a peak at 10.3°±0.2° (2θ) and d value of about 8.6 Å, optionally, another peak at one or more of 4.7°±0.2° (2θ) and d value of about 18.8 Å, and 9.4°±0.2° (2θ) and d value of about 9.4 Å.
A substantially pure crystalline form of a compound selected from:
- wherein the compound comprising a Powder X-ray Diffraction (PXRD) pattern comprising one or more peaks at 10.3°±0.2° (2θ), 4.7°±0.2° (2θ), 9.4°±0.2° (2θ), and 20.1°±0.2° (2θ).
Dependencies are inferred from the claim text.