Hyaluronic acid-based dissolving film, production method thereof, and release liner used for the same

A continuous production method for a hyaluronic acid-based dissolving film, comprising:

• preparing a hyaluronic acid-based solution capable of being carried on a continuous production line;
• supplying a release paper to the continuous production line;
• continuously applying the hyaluronic acid-based solution on the upper side of a release liner supplied to the continuous production line;
• drying the applied hyaluronic acid-based solution on the continuous production line to form a hyaluronic acid-based dissolving film;
• and
• applying a coating solution on the upper side of the release paper and then drying the applied coating solution prior to or after supplying the release paper to the continuous production line,
• wherein the coating solution comprises 10 to 20 wt. % of polyvinyl acetate, 10 to 20 wt. % of water, 50 to 70 wt. % of ethanol, and 1 to 10 wt. % of polyvinyl pyrrolidone,
• wherein the hyaluronic acid-based solution comprises 18 to 26 wt. % of a hyaluronic acid-based compound, 0.2 to 0.6 wt. % of cellulose ether, 0.5 to 1.5 wt. % of polyvinyl alcohol, 0.2 to 0.6 wt. % of polyethylene glycol, 1 to 7 wt. % of polyvinyl pyrrolidone, and
• wherein the hyaluronic acid-based compound has a weight average molecular weight of 10,000 to 50,000 g/mol.