Dosing systems and approaches

A drug delivery system comprising:

• a delivery container including an upper portion, a lower portion, a first side portion, a second side portion, and a tapered region extending between the first side portion and the second side portion, the delivery container including at least one opening formed in the upper portion thereof, the delivery container further including an interior cavity, the tapered region including a surface area between seams defining the interior cavity;
• a first drug insertion port positioned at the lower portion of the delivery container, the first drug insertion port having a luer lock;
• at least one additional drug insertion port positioned at the lower portion of the delivery container, the at least one additional drug insertion port not having a luer lock, wherein at least one of the first drug insertion port and the at least one additional drug insertion port is positioned through the surface area of the tapered region;
• an IV connection port positioned at the lower portion of the delivery container adjacent to a lower portion of the tapered region;
• and
• a rigid container defining an inner volume, the rigid container having an upper portion and a lower portion, the upper portion including at least one mounting post dimensioned to receive the at least one opening of the delivery container to operably secure the delivery container within the inner volume of the rigid container, the lower portion of the rigid container including an opening to accommodate at least one of the IV connection port or an IV line,
• wherein the surface area is downwardly angled from the first side portion toward the IV connection port.