Methods of treatment for Candida auris infections
OwnerJohn E. Edwards, Jr., Shakti Singh +2inventors
InventorsJohn E. Edwards, Jr., Shakti Singh, Ashraf S. Ibrahim, Priya Uppuluri
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Abstract
Disclosed herein are compositions and methods for treating and immunizing against C. auris infection and colonization. The compositions and methods include polypeptides and fragments derived from the C. albicans Als3 protein, homologs thereof, and antibodies or fragments thereof that specifically bind these polypeptides and fragments. Administration of these compositions confers treatment and resistance against C. auris infection and colonization.
Claims14
A method of treating a subject for, immunizing a subject against, preventing in a subject, or inducing production of antibodies in a subject against, a Candida auris infection by administering to the subject an immunogenic amount of a C. auris Als3 polypeptide comprising at least one of SEQ ID NOs:
- 1-7, or an anti-C. auris Als3 antibody.
Dependencies are inferred from the claim text.