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US 12,319,931 B2Granted
Oncolytic virus expressing interferon and application therefor
AssigneeShanghai Yuansong Biotechnology Co. Ltd.
InventorsKangjian Zhang, Xianlong Fang, Jinfa Gu, Xinyuan Liu
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Abstract
Provided is an oncolytic virus expressing interferon. Specifically provided is an oncolytic adenovirus comprising a fusion protein expressing interferon, said oncolytic virus being capable of effectively suppressing tumors in vitro and in vivo.
Claims16
An oncolytic virus comprising a nucleic acid encoding interferon, wherein the nucleic acid comprises a sequence selected from the group consisting of SEQ ID NO:2, 3 and 4.
Dependencies are inferred from the claim text.