Phosphorylcholine group-containing polysiloxane monomer
AssigneeNof Corporation
InventorsYoshiki Tanaka, Shu Takashima, Norio Iwakiri, Yosuke Matsuoka
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AssigneeNof Corporation
InventorsYoshiki Tanaka, Shu Takashima, Norio Iwakiri, Yosuke Matsuoka
Estimating the term…
The phosphorylcholine group-containing polysiloxane monomer of the present invention is represented by the formula (1). In the formula, a represents an integer of 20 to 500, b represents an integer of 1 to 70, c represents an integer of 1 to 70, d represents 0 or 1, p and q each represent 0 or 1, X represents —CH2— or —CH2CH2—, and R represents an alkyl group having 2 to 18 carbon atoms. The present invention provides the phosphorylcholine group-containing polysiloxane monomer which gives, when copolymerized with a polymerizable monomer such as methacrylic acid or a hydrophilic monomer other than methacrylic acid, a polymer that exhibits surface hydrophilicity and sufficient stability as ophthalmic devices.
A phosphorylcholine group-containing polysiloxane monomer represented by the formula (1):
A method for producing a phosphorylcholine group-containing polysiloxane monomer represented by the formula (1), comprising a step of addition reaction of a hydrosilyl group-containing both-terminal methacrylsilicone represented by the formula (4) and a phosphorylcholine compound represented by the formula (6):
A monomer composition containing a phosphorylcholine group-containing polysiloxane monomer represented by the formula (1) in an amount of 10% by mass to 45% by mass, containing a hydroxy group-containing siloxanyl group-containing monomer represented by the formula (8) or the formula (9) in an amount of 10% by mass to 40% by mass, containing methacrylic acid in an amount of 0.1% by mass to 5% by mass, and containing a hydrophilic monomer other than methacrylic acid in an amount of 30% by mass to 70% by mass:
Dependencies are inferred from the claim text.