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US 12,319,700 B2Granted
Monohydrate potassium salt of a thienopyridone derivative and its preparation process
AssigneePoxel
InventorsSébastien Bolze, Marc Lanz, Deniz Arican, Anthony O'Sullivan, Sophie Hallakou-Bozec, Laure Navarre
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Abstract
The invention relates to a process for preparing a monohydrate potassium salt of a 5 thienopyridone derivative. It also relates to a monohydrate potassium salt of a thienopyridone derivative and its use in medicine, in particular for treating or preventing metabolic disorders, such as NASH.
Claims18
A process for preparing a monohydrate potassium salt of formula (I):
- said process comprising the steps of:
- (A) reacting a compound of formula (II) with potassium carbonate in a solution comprising water and a solvent selected from n-butyl acetate and isopropanol:
- (B) forming a precipitate;
- and
- (C) recovering the precipitate obtained in step (B).
2 more elements
A monohydrate potassium salt of formula (I):
Dependencies are inferred from the claim text.