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US 12,318,435 B2Granted
Recombinant protein produced from cholinesterase gene derived from Pseudomonas aeruginosa and the composition comprising the same for treating or preventing a neurological disease
AssigneeSkypeach Co., Ltd
InventorsWon Seog Choi, Moo Hyung Lee, Sang-kyun Park
Life of this patent
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Abstract
The present invention relates to the present invention provides novel recombinant protein produced from cholinesterase gene derived from Pseudomonas aeruginosa and the composition comprising the same for treating or preventing a neurological disease.
Claims9
A recombinant protein of SEQ ID NO:
- 1 (NP protein) that maintains ACHE activity without being inhibited by organophosphorus and carbamate-based nerve agents, which is produced from cholinesterase gene of SEQ ID NO:
- 2 (designated as NP gene hereinafter) derived from Pseudomonas aeruginosa.
A cholinesterase gene of SEQ ID NO:
- 2 (NP gene) encoding the recombinant protein of SEQ ID NO:
- 1 (designated as NP protein hereinafter) that maintains ACHE activity without being inhibited by organophosphorus and carbamate-based nerve agents, which is derived from Pseudomonas aeruginosa.
A pharmaceutical composition comprising the recombinant protein of SEQ ID NO:
- 1, as an active ingredient for treating or preventing a poisoning by nerve agents or a neurological system disorder.
Dependencies are inferred from the claim text.