Tannin-based antiproliferative pharmaceutical

A method of treating oral cancer, the method comprising:

• administering to a patient in need thereof a therapeutically effective amount of a pharmaceuticals composition in solid form,
• wherein the pharmaceutical composition comprises (i) an active ingredient which is 6-O-digalloyl-1,2,3,4-tetra-O-galloyl-μ-D-glucose or a pharmaceutically acceptable salt, solvate, or prodrug thereof, and ii) a pharmaceutically acceptable carrier and/or excipient, which is at least one selected from the group consisting of a buffer, an inorganic salt, a fatty acid, a vegetable oil, a fatty ester, a surfactant, and a polymer, thereby treating the oral cancer,
• wherein the active ingredient accounts for greater than 99% of a total weight of tannins present in the pharmaceutical composition,
• wherein the therapeutically effective amount of the pharmaceutical composition is from 0.1 to 1000 mg/kg of the active ingredient per body weight of the subject, and
• wherein the treating of the oral cancer reduces a tumor size, by diameter, by at least 5%, relative to the tumor size before treating.