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US 12,317,898 B2Granted
Antibacterial surface of metal-organic framework-chitosan composite films
AssigneeColorado State University Research Foundation
InventorsMelissa M. Reynolds, Megan J. Neufeld, Bella H. Neufeld, Alec Lutzke
Life of this patent
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Abstract
A substrate having an antibacterial surface includes a chitosan matrix and water-stable metal-organic frameworks dispersed throughout the chitosan matrix. The water-stable metal-organic frameworks are present in an amount of 5% wt/wt to 20% wt/wt based on total solids of the substrate.
Claims11
A method of reducing adhesion of bacteria on a surface of a substrate, the method comprising:
- forming the surface of the substrate from a material comprising water-stable copper-based metal-organic frameworks dispersed throughout a water-insoluble chitosan matrix, wherein the copper-based metal-organic frameworks are present in an effective amount such that after six hours of exposure to a solution containing the bacteria, bacterial adhesion of the bacteria on the surface is reduced as compared to a surface not containing the material and wherein after six hours of exposure to the solution the material did not release copper in a bactericidal effective amount in the solution.
A method of reducing adhesion of bacteria on a surface of a substrate, the method comprising:
- exposing the substrate comprising water-stable copper-based metal-organic frameworks dispersed throughout a water-insoluble chitosan matrix on the surface to a solution containing the bacteria, wherein the copper-based metal-organic frameworks are present in an effective amount such that after six hours of exposure to the solution, bacterial adhesion on the surface is reduced as compared to a surface not containing the copper-based metal-organic frameworks dispersed throughout the chitosan matrix and wherein after six hours of exposure to the solution the substrate did not release copper in a bactericidal effective amount in the solution.
Dependencies are inferred from the claim text.