Nucleic acid origami structure encapsulated by capsid units
AssigneeGeza Ad Ltd.
InventorIdit Kopatz
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Abstract
Provided are particles of nucleic acid origami structure encapsulated by at least twelve capsid units, compositions comprising the same and uses thereof for delivery of nucleic acids to target cells.
Claims20
A particle comprising a core and a shell, said core comprising at least one nucleic acid origami structure encapsulated by the shell, said shell comprising at least 12 capsid units, the capsid units comprising one or more capsid proteins from a spherical virus, wherein the particle is a virus-like particle having a quasi-spherical geometry and wherein the core comprising the at least one nucleic acid origami structure is nearly spherical or spherical.
Dependencies are inferred from the claim text.