Valve switching system for selectively interconnecting components of a bioprocess installation

A valve switching system for selectively interconnecting components of a bioprocess installation, comprising a valve switching cassette and an actuator block, wherein the valve switching cassette comprises a cassette manifold with at least one fluid flow system of ports and fluid lines, which includes primary ports, communicating with primary fluid lines, and secondary ports, communicating with secondary fluid lines, wherein the valve switching cassette comprises an array of switchable valve units for selectively interconnecting the primary fluid lines with the secondary fluid lines via transfer fluid lines, wherein the valve units each comprise a valve seat, wherein the valve switching cassette comprises a valve membrane structure, that can selectively engage the valve seats as to switch the valve units, wherein the actuator block comprises an actuator block body with an actuator for each valve unit,

• wherein the valve switching cassette comprises a perforated sandwich plate with perforation holes, which sandwich plate is placed between the cassette manifold and the actuator block body, that the valve membrane structure is placed between the cassette manifold and the sandwich plate and wherein a gasket membrane structure is placed between the actuator block body and the sandwich plate and that for selectively switching the valve units, an actuator of the actuator block can act on the valve membrane structure through the perforation holes as to selectively engage the valve seats and that the valve membrane structure comprises at least one valve membrane, which is composed of a first material and that the gasket membrane structure comprises at least one gasket membrane, which is composed of a second material different from the first material.