Dual chamber syringe assembly

A syringe comprising:

• a substantially cylindrically shaped barrel having an open proximal end, a frustoconical shaped distal end, and an inner sidewall, the distal end of the barrel having a needleless connector, a lumen extending through the needleless connector, the lumen being in fluid communication with a cavity of the barrel, the cavity being defined by the open proximal end, the distal end and the inner sidewall;
• a plunger disposed within the barrel having a plunger rod and a distal end, the distal end of the plunger including a connection feature extending distally from the distal end of the plunger;
• a first stopper disposed proximal to a second stopper, the first stopper comprising a proximal end, a distal end and an outer surface, the first stopper further comprising a first plurality of radial ribs disposed on the outer surface of the first stopper, the proximal end of the first stopper including an aperture configured to receive the connection feature of the distal end of the plunger;
• the second stopper disposed proximal to the distal end of the barrel, the second stopper comprising a proximal end, a distal end and an outer surface, the second stopper further comprising a second plurality of radial ribs disposed on the outer surface of the second stopper;
• a first variable volume, the first variable volume being disposed between the first stopper and the second stopper;
• a second variable volume, the second variable volume being between the second stopper and the distal end of the barrel;
• and
• a flow path structure disposed at the distal end of the barrel, the flow path structure extending from the lumen of the needleless connector along the inner sidewall of the barrel, the flow path structure having a first uniform cross-sectional thickness profile extending proximally away from the frustoconical shaped distal end along the inner sidewall of the barrel and a second uniform cross-sectional thickness profile extending along an entire length of the frustoconical shaped distal end, wherein the first uniform cross-sectional thickness profile of the flow path structure is greater than the second uniform cross-sectional thickness profile of the flow path structure, the flow path structure is a protrusion extending from the inner sidewall of the barrel to cause deformation of the second stopper, and the flow path structure extends at least a length of the second stopper, thereby creating a flow path between the second stopper and the inner sidewall of the barrel and creating a flow path from the first variable volume to the lumen of the needleless connector when the second stopper abuts the distal end of the barrel.