Des-acyl ghrelin and analogs as cancer therapies
AssigneeCornell University
InventorKristy A. Brown
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Abstract
The present technology relates to methods for treating, preventing, and/or ameliorating cancer comprising administering a therapeutically effective amount of ghrelin, des-acyl ghrelin, or an analog thereof (e.g, the cyclic peptide analog AZP531) to a subject in need thereof. Kits for use in practicing the methods are also provided.
Claims10
A method for treating cancer in a subject diagnosed with or suffering from cancer, comprising administering to the subject an effective amount of ghrelin, des-acyl ghrelin, or an analog thereof, wherein the cancer does not comprise a mutation in BRAF, HRAS, and KRAS, wherein the subject is a mammal, and wherein the analog is a cyclic peptide comprising the amino acid sequence SPEHORVQ (SEQ ID NO:
- 4).
Dependencies are inferred from the claim text.