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US 12,310,987 B2Granted
Fibrous constructs with therapeutic material particles
AssigneeMerit Medical Systems, Inc.
InventorsJohn Hall, Wayne Mower, John Hellgeth, Rachel Oberg, Doug Friedrichs
Life of this patent
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Abstract
Sheets of material used in medical devices and filters are disclosed. The sheets may include a fibrous mat including a plurality of microfibers. The microfibers may include a polymer matrix and a plurality of additive particles. The additive particles may include carbon material particles, therapeutic micro particles, and any combination thereof. Medical devices and filters that use the sheets are disclosed. Methods of producing the sheets are also disclosed.
Claims20
A fibrous sheet, comprising:
- a mat of fibers comprising a plurality of fibers forming a porous microstructure, wherein the plurality of fibers are formulated from a polymer matrix with a plurality of therapeutic micro or nano particles dispersed throughout the polymer matrix,
- wherein the plurality of therapeutic micro or nano particles are not eluded into a surrounding environment,
- wherein the plurality of therapeutic micro or nano particles comprise a plurality of carbon material particles,
- wherein each of the plurality of carbon material particles are larger than a diameter of each fiber of the mat of fibers, and
- wherein each of the plurality of carbon material particles are entangled by the plurality of fibers.
2 more elements
A fibrous sheet, comprising:
- a mat of fibers, wherein the fibers comprise a polymer matrix and a plurality of carbon material particles that are not eluded into a surrounding environment,
- wherein each of the plurality of carbon material particles are larger than a diameter of fibers, and
- wherein each of the plurality of carbon material particles are entangled by the fibers.
A method of forming a fibrous sheet, comprising:
- obtaining a polymeric mixture comprising a polymer and a plurality of therapeutic micro or nano particles, wherein the plurality of therapeutic micro or nano particles comprise a plurality of carbon material particles;
- extruding the polymeric mixture to form a fibrous mat comprising a plurality of fibers;
- and sintering the fibrous mat,
- wherein the plurality of therapeutic micro or nano particles are configured to not elude into a surrounding environment,
- wherein each of the plurality of carbon material particles are larger than a diameter of fibers, and
- wherein each of the plurality of carbon material particles are entangled by the fibers.
3 more elements
Dependencies are inferred from the claim text.