Preservative removal from eye drops
AssigneeUniversity of Florida Research Foundation, Inc.
InventorsAnuj Chauhan, Kuan-Hui Hsu
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Abstract
A BAK removal device is constructed as a plug of microparticles of a hydrophilic polymeric gel that displays a hydraulic permeability greater than 0.01 Da. The polymer hydrophilic polymeric gel comprises poly(2-hydroxyethyl methacrylate) (pHEMA). The particles are 2 to 100 μm and the plug has a surface area of 30 mm2 to 2 mm2 and a length of 2 mm to 25 mm and wherein the microparticles of a hydrophilic polymeric gel has a pore radius of 3 to 60 μm.
Claims17
A preservative removing device, comprising a porous hydrophilic polymeric matrix suitable to fit an outlet of a container comprising a solution, emulsion, or suspension comprising a preservative and an ophthalmic agent, wherein the porous hydrophilic polymeric matrix is configured to selectively remove the preservative and retain the ophthalmic agent from the solution, emulsion, or suspension that flows through the porous hydrophilic polymeric matrix, wherein the porous hydrophilic polymeric matrix comprises a hydrogel.
Dependencies are inferred from the claim text.