Apparatus and methods for cleaning and/or exchanging medical devices

An apparatus comprising:

• a cassette comprising a plurality of sample acquisition probes;
• a sample processing instrument configured to receive a sample;
• a first plurality of conduits;
• a first chamber comprising a solvent;
• and
• a gas supply;
• wherein:
• the cassette is coupled to the sample processing instrument;
• a first sample acquisition probe is in fluid communication with the sample processing instrument when the cassette is in a first orientation;
• a second sample acquisition probe is in fluid communication with the sample processing instrument when the cassette is in a second orientation;
• and the cassette can be is configured to be moved from the first orientation to the second orientation while the cassette is coupled to the sample processing instrument;
• wherein:
• each sample acquisition probe is in fluid communication with an individual conduit of the first plurality of conduits;
• and each individual conduit of the first plurality of conduits is configured to place a single sample acquisition probe in fluid communication with the sample processing instrument when the cassette is oriented to align the individual conduit with the sample processing instrument;
• and
• wherein each sample acquisition probe in the plurality of sample acquisition probes comprises a reservoir, a first conduit, a second conduit, a third conduit, and a funnel-shaped chamber, wherein:
• the first conduit is in fluid communication with the first chamber;
• the second conduit is in fluid communication with the gas supply;
• the third conduit is in fluid communication with the sample processing instrument;
• the first conduit, the second conduit, and the third conduit each comprises a respective terminus at the reservoir, such that each of the first conduit, the second conduit, and the third conduit are each in fluid in communication with the reservoir;
• and
• the second conduit further comprising the funnel-shaped chamber, wherein the funnel-shaped chamber of the second conduit extending extends from a smaller end to a larger end, the larger end of the funnel-shaped chamber being proximal to the reservoir, and the smaller end of the funnel-shaped chamber being distal from the reservoir, such that the second conduit is in fluid communication with the reservoir via the funnel-shaped chamber of the second conduit.