Therapeutic drug for lipid-peroxidation-induced diseases and screening method for therapeutic drugs for lipid-peroxidation-induced diseases
AssigneesKen-Ichi Yamamada, Fuso Pharmaceutical Industries, Ltd.
InventorsKen-ichi Yamada, Saki Shinto, Tomomi Ide, Keiichi Yamamoto
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Abstract
The present invention provides: an assay method that uses a compound represented by formula (I) as a fluorescent probe molecule and that is for detecting the lipid peroxidation suppression activity of a test compound; an assay kit that uses the assay method; a screening method that uses the assay method; and a pharmaceutical composition that is for the treatment, etc. of diseases (such as age-related macular degeneration) that are induced by lipid peroxidation reactions.
Claims8
An assay kit for detecting lipid peroxidation inhibitory activity of a test compound, comprising:
- a compound represented by formula (I):
- a cultured cell, and
- at least one compound selected from the group consisting of arachidonic acid and tert-butyl hydroperoxide
- in a buffer.
Dependencies are inferred from the claim text.