Back to results
US 12,304,906 B2Granted
Method for preparing lurasidone hydrochloride
AssigneesZhejiang Huahai Pharmaceutical Co., Ltd., Shanghai Syncores Technologies Inc. Ltd.
InventorsYikai Zhang, Junzheng Huang, Hao Lu, Xiaowen Guo, Yafei Jiang, Yuanhai Gao, Luning Huang, Anping Tao, Jianguo An, Hong Gu
Life of this patent
Estimating the term…
Abstract
A method for preparing lurasidone hydrochloride by reacting lurasidone free alkali reacts with hydrochloric acid in a mixed solvent of an alcoholic solvent and an alkyl halide solvent.
Claims12
A method for preparing lurasidone hydrochloride, comprising:
- heating and dissolving lurasidone free base in a mixed solvent of alcoholic solvent and dichloromethane, adding hydrochloric acid solution to carry out a salt-forming reaction;
- and
- cooling, crystallizing, filtering and drying to obtain lurasidone hydrochloride.
Dependencies are inferred from the claim text.