Treating iron deficiency with ferric carboxymaltose
AssigneePharmacosmos Holding A/S
InventorsTobias Sidelmann Christensen, Philip Schaffalitzky De Muckadell, Lars Lykke Thomsen, Claes Christian Strom
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Abstract
The present invention relates to the field of treating iron deficiency with IV iron carbohydrate complexes such ferric carboxymaltose, monitoring or identifying subjects to determine their eligibility for being administered said IV iron carbohydrate complexes, and combining said IV iron carbohydrate complexes with additional drugs in order to mitigate or reduce side effects induced by said IV iron carbohydrate complexes.
Claims29
A method of reducing risk of symptomatic hypophosphatemia associated with repeated treatment of iron deficiency with ferric carboxymaltose in a subject in need thereof, said method comprising,
- administering a dose of ferric carboxymaltose to said subject;
- determining that said subject needs a further dose of ferric carboxymaltose;
- prior to administering the further dose of ferric carboxymaltose, measuring said subject's serum phosphate levels, and if said subject has hypophosphatemia, treating the hypophosphatemia as medically indicated prior to administering the further dose of ferric carboxymaltose;
- and
- administering the further dose of ferric carboxymaltose to said subject.
Dependencies are inferred from the claim text.