Back to results
US 12,302,902 B2Granted
Antimicrobial compositions, including antimicrobial hydrogels, effective against mature biofilms
AssigneeCorMedix Inc.
InventorRobert DiLuccio
Life of this patent
Estimating the term…
Abstract
A method for the prevention or elimination of biofilm microorganisms on at least one surface of a medical device, the method comprising the steps of: (a) providing a biofilm-active composition having at least one biofilm-active agent; and (b) delivering the biofilm-active composition to the medical device in an amount sufficient to prevent or eliminate the biofilm microorganisms on at least one surface of the medical device.
Claims5
A method for killing Pseudomonas aeruginosa on at least one surface of a catheter, the method comprising the steps of:
- (a) providing a bio-film active composition comprising:
- taurolidine, wherein the concentration of the taurolidine, is 0.5% by weight, 1.0% by weight, 1.5% by weight, or 3.0% by weight of the total weight of the bio-film active composition;
- a biofilm-penetrating agent comprising myristic acid, wherein the concentration of the myristic acid is about 1.5% by weight of the total weight of the bio-film active composition;
- and a base material, wherein the base material comprises a hydrogel comprising hyaluronic acid having a molecular weight of 750 kDa to 1.0 MDa;
- and
- (b) delivering the bio-film active composition to the at least one surface of a catheter in a sufficient amount and for a sufficient period of time to kill Pseudomonas aeruginosa on at least one surface of the catheter.
3 more elements
Dependencies are inferred from the claim text.