Needle assembly and a needle receiving assembly with integrated alignment, a capillary injection assembly, system and method

A connection assembly configured to introduce a fluid from a needle to a fluid conducting element, the connection assembly comprising:

• a) a needle assembly configured to connect the needle to a needle receiving assembly, wherein the needle assembly comprises:
• the needle, wherein the needle includes an axial direction along a length of the needle, a radial direction, and a tip, wherein the radial direction is perpendicular to the axial direction;
• a needle housing, wherein the needle occupies a part of a cavity of the needle housing, the needle housing comprising an aligning component configured to increase alignment in the radial direction between the needle and the needle receiving assembly upon contact between the aligning component and the needle receiving assembly;
• and
• b) the needle receiving assembly configured to receive the fluid from the needle, the needle receiving assembly comprising:
• the fluid conducting element comprising:
• a fluid conducting element proximal section and a fluid conducting element proximal end;
• and
• a sealing element, wherein the sealing element is configured to receive the needle;
• wherein the fluid conducting element housing comprises a lateral protruding portion, and wherein the lateral protruding portion comprises an inner lateral surface that laterally surrounds a cavity of the fluid conducting element housing;
• wherein the aligning component comprises an aligning inner surface formed by at least a portion of the inner lateral surface of the lateral protruding portion;
• wherein the fluid conducting element housing comprises a central protruding portion, and wherein the central protruding portion protrudes proximally beyond a base of the fluid conducting element housing;
• and
• wherein the lateral protruding portion protrudes proximally beyond the central protruding portion.

A sampler configured to pick up a fluid, wherein the sampler comprises a fluid conducting element and a needle, wherein the sampler comprises a needle receiving assembly and a needle assembly,

• a) the needle assembly configured to connect the needle to the needle receiving assembly, wherein the needle assembly comprises:
• the needle, wherein the needle includes an axial direction along a length of the needle, a radial direction, and a tip, wherein the radial direction is perpendicular to the axial direction;
• a needle housing, wherein the needle occupies a part of a cavity of the needle housing, the needle housing comprising an aligning component configured to increase alignment in the radial direction between the needle and the needle receiving assembly upon contact between the aligning component and the needle receiving assembly;
• and
• b) the needle receiving assembly configured to receive the fluid from the needle, the needle receiving assembly comprising:
• the fluid conducting element comprising:
• a fluid conducting element proximal section and a fluid conducting element proximal end;
• and
• a sealing element, wherein the sealing element is configured to receive the needle;
• wherein the fluid conducting element housing comprises a lateral protruding portion, and wherein the lateral protruding portion comprises an inner lateral surface that laterally surrounds a cavity of the fluid conducting element housing;
• wherein the aligning component comprises an aligning inner surface formed by at least a portion of the inner lateral surface of the lateral protruding portion;
• wherein the fluid conducting element housing comprises a central protruding portion, and wherein the central protruding portion protrudes proximally beyond a base of the fluid conducting element housing;
• and
• wherein the lateral protruding portion protrudes proximally beyond the central protruding portion.

A system for analyzing a liquid, the system comprising

• a) a liquid chromatography to analyze the liquid, and
• b) a sampler configured to pick up a fluid, wherein the sampler comprises a fluid conducting element and a needle, wherein the sampler comprises a needle receiving assembly and a needle assembly,
• i) the needle assembly configured to connect the needle to the needle receiving assembly, wherein the needle assembly comprises:
• the needle, wherein the needle includes an axial direction along a length of the needle, a radial direction, and a tip, wherein the radial direction is perpendicular to the axial direction;
• a needle housing, wherein the needle occupies a part of a cavity of the needle housing, the needle housing comprising an aligning component configured to increase alignment in the radial direction between the needle and the needle receiving assembly upon contact between the aligning component and the needle receiving assembly;
• and
• ii) the needle receiving assembly configured to receive the fluid from the needle, the needle receiving assembly comprising:
• the fluid conducting element comprising:
• a fluid conducting element proximal section and a fluid conducting element proximal end;
• and
• a sealing element, wherein the sealing element is configured to receive the needle;
• wherein the fluid conducting element housing comprises a lateral protruding portion, and wherein the lateral protruding portion comprises an inner lateral surface that laterally surrounds a cavity of the fluid conducting element housing;
• wherein the aligning component comprises an aligning inner surface formed by at least a portion of the inner lateral surface of the lateral protruding portion;
• wherein the fluid conducting element housing comprises a central protruding portion, and wherein the central protruding portion protrudes proximally beyond a base of the fluid conducting element housing;
• and
• wherein the lateral protruding portion protrudes proximally beyond the central protruding portion.