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US 12,298,239 B2Granted
Interferometric detection and quantification system and methods of use in aquatics
AssigneeSalvus, LLC
InventorsRon Levin, Clinton Beeland, James LeFiles, Joseph Egan, Timothy Zollers, Jacob Thompson
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Abstract
A point of use analyte detection and quantification system for aquatic applications is provided. Related methods are also provided.
Claims20
A method of detecting and quantifying the level of analyte in an aquatic test sample, the method comprising the steps of:
- collecting an aquatic test sample containing one or more analytes;
- introducing the aquatic target sample to a portable interferometric system;
- initiating waveguide interferometry on the aquatic test sample;
- and
- processing any data resulting from the waveguide interferometry,
- wherein the interferometric system comprises:
- an optical assembly unit, the optical assembly unit comprising a light unit and a detector unit each adapted to fit within a portable housing unit;
- and
- a cartridge system adapted to be inserted in the housing unit and removed after one or more uses, the cartridge system comprising:
- an interferometric chip including one or more waveguide channels having a sensing layer thereon, the sensing layer adapted to selectively bind or otherwise be selectively disturbed by one or more analytes within the aquatic test sample;
- and
- a flow cell wafer;
- and
- a cartridge housing enclosing the interferometric chip and flow cell wafer;
- and
- an alignment means for aligning the cartridge system within a cartridge recess in the optical assembly unit upon insertion thereby providing optical and microfluidic alignment of the interferometric chip and flow cell wafer.
13 more elements
Dependencies are inferred from the claim text.