Chromosomal assessment to diagnose urogenital malignancy in dogs

A kit for detecting a urogenital malignancy in a dog, the kit comprising nucleic acid probes, primers, or pairs of primers, wherein the nucleic acid probes, primers, or pairs of primers consist of:

• a first nucleic acid probe, primer, or pair of primers capable of specifically detecting canine chromosome CFA 13 in a biological sample comprising neoplastic cells obtained from a dog;
• a second nucleic acid probe, primer, or pair of primers capable of specifically detecting canine chromosome CFA 19 in the biological sample;
• a third nucleic acid probe, primer, or pair of primers capable of specifically detecting canine chromosome CFA 36 in the biological sample;
• and optionally a fourth nucleic acid probe, primer, or pair of primers capable of specifically detecting a dog chromosome other than CFA 13, CFA 19, and CFA 36 and for measuring a copy number of the dog chromosome other than CFA 13, CFA 19, and/or CFA 36 to serve as a copy number control,
• and further wherein the first, second, and third, and optionally the fourth of nucleic acid probes, primers, or pairs of primers are differentially fluorescently labeled.