Porcine rotavirus
AssigneeIntervet Inc.
InventorsAd De Groof, Paul Vermeij, Cornelia Maria Van der Hoek, Martin Deijs
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Abstract
The present invention pertains to a novel rotavirus, especially an isolated virus, which is a member of the sub-species of porcine group B rotavirus (porcine RVB), causing diarrheal disease in pigs, to DNA fragments and corresponding proteins of the said virus, to vaccines on the basis of said virus, DNA and/or protein and to antibodies reactive with said virus and/or protein and diagnostic test kits for the detection of said virus.
Claims19
An isolated rotavirus which is a member of the sub-species of porcine group B rotaviruses genotype G12, which in its wild type form causes diarrhea in pigs, said virus being characterized in that it has a viral genome comprising an open reading frame having a nucleotide sequence corresponding to the nucleotide sequence depicted in SEQ ID NO:
- 1 or a nucleotide sequence having a level of identity of at least 90% therewith.
A nucleic acid fragment comprising an open reading frame, said open reading frame comprising at least 200 nucleotides, characterized in that said nucleic acid fragment has a nucleotide sequence that corresponds to a sequence having a level of identity of at least 90% to the nucleotide sequence depicted in SEQ ID NO:
- 1.
An outer viral capsid glycoprotein VP7 or a fragment thereof, characterized that it is a protein according to SEQ ID NO:2, or a protein having a level of identity of at least 93% therewith.
Dependencies are inferred from the claim text.