Device, systems, and methods of applying a treatment solution to a treatment site

A non-transitory computer-readable medium storing instructions that, when executed by a processor, cause a handheld portable electrostatic applicator to perform operations, the operations comprising:

• electrostatically charging, by a cartridge assembled with the handheld portable electrostatic applicator, a treatment solution, the handheld portable electrostatic applicator comprising a housing, the cartridge removably disposed in the housing, the cartridge comprising a cartridge housing, at least one electrode to electrostatically charge and ionize molecules of the treatment solution of the cartridge, and a nozzle positioned at a distal end of the cartridge housing, the nozzle of the cartridge being configured to deliver the electrostatically charged treatment solution and configured to be in fluid communication with an air supply tube in fluid communication with a pump in the housing;
• and
• pressurizing, by a pump of the handheld portable electrostatic device, the treatment solution contained in the cartridge.