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US 12,296,071 B2Granted
Functionalisation of medical devices
AssigneeConvatec Technologies Inc.
InventorsRachel Zimet Pytel, Neal Robert Carty
Life of this patent
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Abstract
Methods of modifying medical devices and medical devices are disclosed. One embodiment of a method of modifying a medical device includes functionalizing a surface of the medical device using cold plasma. One embodiment of a medical device is obtained by a method of modifying a device that includes functionalizing a surface of the medical device using cold plasma.
Claims14
A method of modifying a medical device, the method comprising:
- functionalizing a surface of the medical device using cold plasma,
- wherein:
- functionalizing the surface of the medical device using cold plasma comprises contacting the surface with cold plasma to provide a plasma-treated surface and performing cold plasma treatment at a temperature between 15° C. and 40° C.,
- contacting the surface with cold plasma comprises introducing a monomer to cold plasma to create monomer plasma and applying the monomer plasma to the surface to provide the plasma-treated surface,
- the method further comprises mixing the monomer with a precursor gas stream consisting of nitrogen gas,
- functionalizing the surface using cold plasma comprises functionalizing the plasma-treated surface with a polymer, and
- the polymer or the monomer is a polyalkylene glycol having a reactive end group.
4 more elements
A method of modifying a medical device, the method comprising:
- functionalizing a surface of the medical device using cold plasma,
- wherein:
- functionalizing the surface of the medical device using cold plasma comprises contacting the surface with cold plasma to provide a plasma-treated surface and performing cold plasma treatment at a temperature between 15° C. and 40° C.,
- contacting the surface with cold plasma comprises introducing a monomer to cold plasma to create monomer plasma and applying the monomer plasma to the surface to provide the plasma-treated surface,
- the method further comprises mixing the monomer with a precursor gas stream consisting of nitrogen gas,
- functionalizing the surface using cold plasma comprises functionalizing the plasma-treated surface with a polymer,
- the polymer or the monomer is a polyalkylene glycol having a reactive end group, and
- wherein the polymer or the monomer is selected from the group including an acrylate-functionalized polyalkylene glycol and an alkylacrylate polyalkylene glycol.
5 more elements
A method of modifying a medical device, the method comprising:
- functionalizing a surface of the medical device using cold plasma,
- wherein:
- functionalizing the surface of the medical device using cold plasma comprises contacting the surface with cold plasma to provide a plasma-treated surface and performing cold plasma treatment at a temperature between 15° C. and 40° C.,
- contacting the surface with cold plasma comprises introducing a monomer to cold plasma to create monomer plasma and applying the monomer plasma to the surface to provide the plasma-treated surface,
- the method further comprises mixing the monomer with a precursor gas stream consisting of nitrogen gas,
- functionalizing the surface using cold plasma comprises functionalizing the plasma-treated surface with a polymer,
- the polymer or the monomer is a polyalkylene glycol having a reactive end group,
- wherein the polymer or the monomer is selected from the group including an acrylate-functionalized polyalkylene glycol and an alkylacrylate polyalkylene glycol, and
- wherein the polymer or the monomer is selected from the group including an acrylate- or methacrylate-functionalized polyethylene or polypropylene glycol.
6 more elements
A method of modifying a medical device, the method comprising:
- combining a monomer with a cold plasma;
- creating a monomer plasma of the monomer;
- and
- graft polymerizing the monomer plasma onto a surface of the medical device,
- wherein combining the monomer with the cold plasma comprises combining a monomer having the following formula with the cold plasma:
2 more elements
A method of modifying a medical device, the method comprising:
- combining a monomer with a cold plasma;
- creating a monomer plasma of the monomer;
- and
- graft polymerizing the monomer plasma onto a surface of the medical device to create a hydrophilic surface or a hydrophobic surface,
- wherein graft polymerizing the monomer plasma onto the surface of the medical device comprises performing cold plasma treatment at a temperature between 15° C. and 40° C.,
- wherein combining the monomer with the cold plasma comprises mixing the monomer with a precursor gas stream consisting of nitrogen gas, and
- wherein the monomer is a polyalkylene glycol having a reactive end group.
4 more elements
Dependencies are inferred from the claim text.