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US 12,296,069 B2Granted
Tissue construct, methods of producing and using the same
AssigneePresident and Fellows of Harvard College
InventorsMark Skylar-Scott, Sebastien Uzel, Jennifer Lewis
Life of this patent
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Abstract
Described are methods for producing tissue constructs, tissue constructs produced by the methods, and their use. The described method of producing a tissue construct comprises providing a granular tissue, depositing one or more filaments on or in the granular tissue, each filament comprising an ink, and gelling or fusing the granular tissue, thereby producing the tissue construct.
Claims36
A method of producing a tissue construct, comprising:
- compacting embryoid bodies, organoids, cells, cell spheroids, multicellular tissue aggregates, or a combination thereof to form a granular tissue comprising a compacted assembly of embryoid bodies, organoids, cells, cell spheroids, multicellular tissue aggregates, or a combination thereof;
- providing the granular tissue;
- depositing one or more filaments on or in the granular tissue, each filament comprising an ink;
- and
- gelling or fusing the granular tissue, thereby producing the tissue construct.
2 more elements
Dependencies are inferred from the claim text.