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US 12,296,011 B2Granted
Methods for photodynamic therapy
AssigneeSun Pharmaceutical Industries Limited
InventorsScott Lundahl, Michael Guttadauro
Life of this patent
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Abstract
A method of enhancing penetration of a topical composition of 5-aminolevulinic acid (ALA) into tissue for photodynamic therapy includes topically applying ALA to a treatment area to be treated with photodynamic therapy. The method further includes, after the ALA is applied to the treatment area, covering the treatment area with a low density polyethylene barrier. The treatment area is covered with the low density polyethylene barrier prior to light treatment to minimize transepidermal water loss from the treatment area.
Claims6
A method of treating a lesion, the method comprising:
- providing, via an applicator, a topical composition comprising 5-aminolevulinic acid (ALA);
- applying the topical composition comprising the ALA onto a portion of skin containing the lesion, the portion of skin being on an extensor surface of a patient's body, wherein applying the topical composition via the applicator comprises controlling a dispersion of the topical composition;
- providing, via the dispersion of the topical composition, uniform wetting of the portion of skin containing the lesion;
- incubating the portion of the skin containing the lesion;
- applying a barrier directly on the wetted portion of the skin;
- and
- irradiating, via a light source, the portion of skin for a first time period.
4 more elements
Dependencies are inferred from the claim text.