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US 12,295,397 B2Granted
Dietary peptides
AssigneeDiet4Life APS
InventorsJan Stagsted, Jiehui Zhou, Randi Jessen, Johan Palmfeldt, Erik Torngaard Hansen
Life of this patent
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Abstract
The present invention relates to novel peptides, composition comprising such peptides including nutritional supplements and methods for inducing satiation and satiety, for weight management and preventing or reducing the incidence of obesity, or for preventing or reducing cardiovascular diseases, atherosclerosis, hypertension, hepatosteatosis, cancer and/or diabetes.
Claims21
A method of, in a subject in need thereof, promoting satiety, comprising enteral administering to the subject in need thereof a polypeptide comprising or consisting of the amino acid sequence
- AA1-AA2-AA3-AA4-P—Y—I-L (formula III, SEQ ID NO:3),
- wherein AA1 is an optional amino acid selected from A, L, I, and V;
- AA2 is an optional amino acid selected from S, T, G, A, N, E and D;
- AA3 is an optional amino acid selected from D, R, K, E, and G;
- and AA4 is an amino acid selected from K and R;
- which polypeptide is not more than 50 amino acids in length;
- or a variant thereof with a sequence identity of at least 80%, wherein the polypeptide is a linear sequence of amino acids comprising only standard peptide bonds,
- or administering a composition comprising said polypeptide.
5 more elements
Dependencies are inferred from the claim text.