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US 12,291,652 B2Granted
Zwitterionic double network hydrogels
AssigneeUniversity of Washington
InventorsShaoyi Jiang, Hsiang-Chieh Hung, Dianyu Dong, Caroline Tsao, Chenjue Tang, Joel MacArthur
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Abstract
Zwitterionic double network hydrogels, methods for making zwitterionic double network hydrogels, methods for using zwitterionic double network hydrogels, and articles made from and coated with zwitterionic double network hydrogels.
Claims37
A double network hydrogel, comprising:
- (a) a first polymeric network comprising a first crosslinked zwitterionic polymer having from about 50 to about 100 mole percent zwitterionic moieties;
- and
- (b) a second polymeric network comprising a second crosslinked zwitterionic polymer having from about 50 to about 100 mole percent zwitterionic moieties,
- wherein the double network hydrogel has a compressive fracture stress of greater than about 0.9 MPa.
1 more element
A double network hydrogel, comprising:
- (a) a first polymeric network comprising a first chemically crosslinked zwitterionic polymer having from about 50 to about 100 mole percent zwitterionic moieties;
- and
- (b) a second polymeric network comprising a second chemically crosslinked zwitterionic polymer having from about 50 to about 100 mole percent zwitterionic moieties.
A microgel, comprising a double network hydrogel, the double network hydrogel comprising:
- (a) a first polymeric network comprising a first crosslinked polymer, wherein the first polymeric network is a hydrogel;
- and
- (b) a second polymeric network comprising a second crosslinked zwitterionic polymer having from about 50 to about 100 mole percent zwitterionic moieties, wherein the double network hydrogel has a compressive fracture stress of greater than about 0.9 MPa;
- or
- (c) a first polymeric network comprising a first crosslinked polymer, wherein the first polymeric network is a hydrogel;
- and
- (d) a second polymeric network comprising a chemically crosslinked poly(sulfobetaine) having from about 50 to about 100 mole percent zwitterionic moieties.
4 more elements
A surface coating for a substrate, comprising a double network hydrogel, the double network hydrogel comprising:
- (a) a first polymeric network comprising a first crosslinked polymer, wherein the first polymeric network is a hydrogel;
- and
- (b) a second polymeric network comprising a second crosslinked zwitterionic polymer having from about 50 to about 100 mole percent zwitterionic moieties, wherein the double network hydrogel has a compressive fracture stress of greater than about 0.9 MPa;
- or
- (c) a first polymeric network comprising a first crosslinked polymer, wherein the first polymeric network is a hydrogel;
- and
- (d) a second polymeric network comprising a chemically crosslinked poly(sulfobetaine) having from about 50 to about 100 mole percent zwitterionic moieties.
4 more elements
Dependencies are inferred from the claim text.