Sample analysis with mirrors
AssigneePresident and Fellows of Harvard College
InventorsShencheng Ge, Yunzhe Wang, Nicolas J. Deshler, Daniel J. Preston, George M. Whitesides
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Abstract
A device is disclosed, including: a plate including a sample deposition tube adapted to receive a sample comprising one or more analytes, the sample deposition tube defining a vertical axis substantially perpendicular to a main surface of the plate; and a mirror positioned to project, substantially parallel to the main surface of the plate, an image of the sample deposition tube along its vertical axis, so as to allow determination of the vertical location of the one or more analytes inside the sample deposition tube. Methods for determining the density of one or more analytes using various embodiments of the device are also described.
Claims22
A device, comprising:
- a plate comprising a sample deposition tube adapted to receive a sample comprising one or more analytes, the sample deposition tube defining a vertical axis substantially perpendicular to a main surface of the plate;
- and
- a mirror positioned to project, substantially parallel to the main surface of the plate, an image of the sample deposition tube along its vertical axis, so as to allow determination of the vertical location of the one or more analytes inside the sample deposition tube.
A method comprising:
- providing a device comprising:
- a plate comprising one or more sample deposition tubes adapted to receive one or more samples comprising one or more analytes, each of the one or more sample deposition tubes defining a vertical axis substantially perpendicular to a main surface of the plate;
- and
- one or more mirrors positioned to project, substantially parallel to the main surface of the plate, an image of each of the one or more sample deposition tubes along its vertical axis, so as to allow determination of the vertical location of the one or more analytes inside each of the one or more sample deposition tubes;
- depositing a sample comprising one or more analytes into one or more of the sample deposition tubes;
- allowing the one or more analytes to migrate to a position at least partially determined by its density;
- and
- projecting, substantially parallel to the main surface of the plate, an image of each of the one or more sample deposition tubes along its vertical axis to determine the vertical location of the one or more analytes inside each of the one or more sample deposition tubes.
Dependencies are inferred from the claim text.