Binding proteins for the enzyme acid alpha glucosidase (GAA) and uses thereof
AssigneeNavigo Proteins GmbH
InventorsErik Fiedler, Mathias Kahl, Jonathan Lotze, Eva Bosse-Doenecke
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AssigneeNavigo Proteins GmbH
InventorsErik Fiedler, Mathias Kahl, Jonathan Lotze, Eva Bosse-Doenecke
Estimating the term…
The present invention relates to the field of protein purification and relates in particular to novel proteins that bind specifically to acid alpha glucosidase (GAA). The invention further relates to fusion proteins comprising novel proteins that bind specifically to GAA. In addition, the invention relates to affinity matrices comprising the GAA binding proteins of the invention. The invention also relates to a use of these GAA binding proteins or affinity matrices for affinity purification of GAA and to methods of affinity purification of GAA using the GAA binding proteins of the invention. Further uses relate to analytical methods for the determination of GAA in liquids.
An acid alpha-glucosidase (GAA) binding protein comprising one or more GAA binding domains wherein at least one domain comprises the amino acid sequence of SEQ ID NO:
Dependencies are inferred from the claim text.