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US 12,281,110 B2Granted
Processes for preparing an FGFR inhibitor
AssigneePrincipia Biopharma Inc.
InventorsJiang Zhu, Mohammad Masjedizadeh
Life of this patent
Estimating the term…
Abstract
Disclosed herein are processes for preparing 8-(3-(4-acryloylpiperazin-1-yl)propyl)-6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)pyrido[2,3-d]pyrimidin-7(8H)-one and FGFR inhibitor, as well as polymorphs and/or salt forms thereof.
Claims19
A crystalline free base of a compound of formula:
An amorphous free base of a compound of formula:
A crystalline hydrochloride salt or a crystalline maleate salt of a compound of formula:
Dependencies are inferred from the claim text.