Antibacterial composition and uses thereof
AssigneeErytech Pharma
InventorsCindy Fevre, Hélène Blois, Mathieu Medina
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Abstract
The present invention relates to bacteriophage therapy. More particularly, the present invention relates to novel bacteriophages having a high specificity against Staphylococcus aureus strains, their manufacture, components thereof, compositions comprising the same and the uses thereof in phage therapy and as companion diagnostic.
Claims11
An antibacterial composition comprising at least one bacteriophage having lytic activity against at least one Staphylococcus aureus (S. aureus) strain and a pharmaceutically acceptable excipient or carrier,
- said at least one bacteriophage being selected from the bacteriophages having a genome comprising the nucleotide sequence of any one of SEQ ID NOs:
- 1 to 4 or a sequence having at least 95% identity thereto, and
- said pharmaceutically acceptable excipient or carrier comprising a preservative in an amount effective to preserve the activity of the bacteriophage.
A method for preparing an antibacterial composition comprising producing at least one bacteriophage having lytic activity against at least one Staphylococcus aureus (S. aureus) strain, said at least one bacteriophage being selected from the bacteriophages having a genome comprising the nucleotide sequence of any one of SEQ ID NOs:
- 1 to 4 or a sequence having at least 95% identity thereto, and combining said bacteriophage with a pharmaceutically suitable carrier or excipient.
Dependencies are inferred from the claim text.