Compositions and methods of a dihydroisoxazole compound that reduces ectoparasite infestations on fish

Abstract

Ectoparasite infestations in fish farming can pose significant challenges and issues for aquaculture operations. This disclosure generally relates to treatment or control of ectoparasite infestations (such as sea lice infestations) on fish (such as salmonids) using a particular dosing regimen of an isoxazoline. In particular, the dosing regimen includes oral administration of the active ingredient: (S)-3-methyl-N-(2-oxo-2-(prop-2-yn-1-ylamino) ethyl)-5-(5-(3,4,5-trichlorophenyl)-5-(trifluoromethyl)-4,5-dihydroisoxazol-3-yl) thiophene-2-carboxamide, including salts, or N-oxide, or solvates thereof, of structural formula The active ingredient may be administered at a dosage (i.e., in a dose) of from about 0.025 mg/kg/d to about 0.250 mg/kg/d. The dosing regimen may include oral administration from about 3 to about 10 consecutive days.

Dependencies are inferred from the claim text.