Methods and compositions to inhibit dependence on opioids
AssigneeSen-Jam Pharmaceutical LLC
InventorsJacqueline M. Iversen, Thomas A. Dahl
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Abstract
The present invention provides a method of inhibiting dependence to an opioid by a human subject in need thereof. The method comprises administering an effective amount of a pharmaceutical composition to the subject during opioid therapy. The pharmaceutical composition comprises a) a non-steroidal anti-inflammatory drug (NSAID); and b) a co-agent selected from the group consisting of: fexofenadine, ketotifen, desloratadine, cetirizine, salts thereof and combinations thereof.
Claims12
A method of inhibiting dependence to an opioid by a human subject in need thereof, comprising:
- administering an effective amount of a pharmaceutical composition to the subject during opioid therapy,
- wherein the pharmaceutical composition comprises:
- a) a non-steroidal anti-inflammatory drug (NSAID);
- and
- b) a co-agent selected from the group consisting of:
- fexofenadine, ketotifen, desloratadine, cetirizine, salts thereof and combinations thereof;
- wherein dependence to an opioid is inhibited in the human subject.
A method of inhibiting dependence to an opioid by a human subject in need thereof, comprising:
- administering to the subject an effective amount of a pharmaceutical composition during an opioid therapy, wherein the pharmaceutical composition consists of active agents:
- a) about 1200 mg to about 1600 mg of ibuprofen, and
- b) about 0.5 mg to about 3 mg ketotifen,
- wherein dependence to an opioid is inhibited in the human subject.
Dependencies are inferred from the claim text.