Antibodies that bind interleukin-10 receptor-2 peptides, compositions, and methods of use thereof
AssigneeWisconsin Alumni Research Foundation
InventorsMaria K. Dashek, Mark E. Cook
Life of this patent
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Abstract
Described herein are interleukin-10 receptor-2 peptides, antibodies that bind the peptides, compositions including the peptides and antibodies and methods of use of the peptides and antibodies. The interleukin-10 receptor-2 peptide consists of an 8-15 amino acid sequence that includes SEQ ID NO: 1 ((I/V)P(P/K/V/E)P(E/K/R/Q)N(A/V)R), SEQ ID NO: 2 ((S/L/V)PAF(A/P)(K/Q)(G/T/E)(N/T/D)), or SEQ ID NO: 3 (PP(G/T/Q/V)(V/T/A)(R/H/T/S)(GN/NHP/SAA)).
Claims21
An isolated antibody that specifically binds an interleukin-10 receptor-2 peptide, wherein the interleukin-10 receptor-2 peptide is selected from the group consisting of SEQ ID NOs:
- 4, 5, 8, 14, 16 and 17, wherein the antibody is a polyclonal avian egg yolk IgY antibody preparation produced by inoculating laying hens with the peptide.
A dried egg yolk comprising an antibody that specifically binds an interleukin-10 receptor-2 peptide, wherein the interleukin-10 receptor-2 peptide is selected from the group consisting of SEQ ID NOs:
- 4, 5, 8, 14, 16 and 17, wherein the antibody is a polyclonal avian egg yolk IgY antibody preparation produced by inoculating laying hens with the peptide.
A composition comprising dried egg yolk, wherein the dried egg yolk comprises an antibody that specifically binds an interleukin-10 receptor-2 peptide, wherein the interleukin-10 receptor-2 peptide is selected from the group consisting of SEQ ID NOs:
- 4, 5, 8, 14, 16 and 17, wherein the antibody is a polyclonal avian egg yolk IgY antibody preparation produced by inoculating laying hens with the peptide.
Dependencies are inferred from the claim text.