Compositions and methods for treating retinal degradation
AssigneeUniversity of Kentucky Research Foundation
InventorsJayakrishna Ambati, Benjamin Fowler
Life of this patent
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Abstract
The present disclosure relates to compositions and methods for treating retinal damage and/or retinal degradation. More specifically, this disclosure relates to methods for treating degradation of the retinal pigment epithelium by administering compositions comprising a nucleoside and/or a nucleoside or nucleotide reverse transcriptase inhibitor.
Claims17
A method of blocking inflammasome activation, the method comprising administering to a patient in need thereof a nucleoside reverse transcriptase inhibitor (NRTI), whereby the NRTI blocks inflammasome activation, wherein the NRTI is selected from stavudine (d4T), lamivudine (3TC), abacavir (ABC), 5′-methoxy-d4T, or combinations thereof.
Dependencies are inferred from the claim text.