Paramagnetic immunobeads for the isolation of human adipose-derived stem cells
AssigneeUniversity of Florida Research Foundation, Inc.
InventorsJohn D. Murray, Edward W. Scott
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Abstract
Disclosed herein are compositions, devices, and methods for isolating human Adipose-derived stem cells (ASCs) without either electricity or enzymatic digestion. In particular, a paramagnetic immunobead (PIB) for isolating human ASCs is disclosed. In some embodiments, the PIB displays on its surface one or more antibodies that selectively bind ASC-specific antigens. Also disclosed is a method for isolating human ASCs using the disclosed PIBs.
Claims5
A paramagnetic immunobead (PIB) for isolating human adipose-tissue derived stem cells, consisting of a magnetic material displaying on its surface a first antibody that selectively binds human CD90, a second antibody that selectively binds human CD44, a third antibody that selectively binds human CD105, and a fourth antibody that selectively binds human CD73, wherein the magnetic material is a paramagnetic spherical polymer particle.
Dependencies are inferred from the claim text.