Systems and methods for multiplanar radiation treatment

A system for delivering radiation treatment to a subject using a radiation delivery device that includes a plurality of components, the plurality of components including one or more first components and one or more second components, the one or more first components including at least one of a collimator or multi-leaf collimator leaves, the one or more second components at least including a couch and a gantry, the system comprising:

• at least one storage device storing a set of instructions;
• and
• at least one processor configured to communicate with the at least one storage device, wherein when executing the set of instructions, the at least one processor is configured to direct the system to perform operations including:
• defining a preliminary trajectory including a plurality of control points, the preliminary trajectory being defined by a position parameter of each second component for each control point without defining a position parameter of each first component for each control point, the position parameter of each second component for each control point is determined based on a position, a shape, and a size of a region of interest;
• generating a treatment plan by optimizing, for each of the plurality of control points, the position parameter of each first component and an intensity;
• decomposing the treatment plan into a delivery trajectory including the plurality of control points, each of the plurality of control points being further associated with the optimized intensity, the optimized position parameter of each first component, and a motion parameter of each second component;
• and
• instructing the radiation delivery device to deliver the treatment plan to the subject according to the delivery trajectory.

A non-transitory computer readable medium, comprising a set of instructions for delivering radiation treatment to a subject using a radiation delivery device that includes a plurality of components, the plurality of components including one or more first components and one or more second components, the one or more first components including at least one of a collimator or multi-leaf collimator leaves, the one or more second components at least including a couch and a gantry, wherein when executed by at least one processor, the set of instructions direct the at least one processor to effectuate a method, the method comprising:

• defining a preliminary trajectory including a plurality of control points, the preliminary trajectory being defined by a position parameter of each second component for each control point without defining a position parameter of each first component for each control point, the position parameter of each second component for each control point is determined based on a position, a shape, and a size of a region of interest;
• generating a treatment plan by optimizing, for each of the plurality of control points, the position parameter of each first component and an intensity;
• decomposing the treatment plan into a delivery trajectory including the plurality of control points, each of the plurality of control points being further associated with the optimized intensity, the optimized position parameter of each first component, and a motion parameter of each second component;
• and
• instructing the radiation delivery device to deliver the treatment plan to the subject according to the delivery trajectory.