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US 12,268,756 B2Granted
Biocompatible magnetic materials
AssigneeMegaPro Biomedical Co., Ltd.
InventorsWen-Yuan Hsieh, Yuan-Hung Hsu, Chia-Wen Huang, Ming-Cheng Wei, Chih-Lung Chen, Shian-Jy Wang
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Abstract
A biocompatible magnetic material containing an iron oxide nanoparticle and one or more biocompatible polymers, each having formula (I) below, covalently bonded to the iron oxide nanoparticle: in which each of variables R, L, x, and y is defined herein, the biocompatible magnetic material contains 4-15% Fe(II) ions relative to the total iron ions. Also disclosed in a method of preparing the biocompatible magnetic material.
Claims16
A biocompatible magnetic material comprising:
- an iron oxide oleic acid nanoparticle;
- and
- one or more biocompatible polymers, each having formula (I) below, covalently bonded to the iron oxide oleic acid nanoparticle:
- in which
- R is H, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C3-C10 cycloalkyl, C1-C10 heterocycloalkyl, aryl, heteroaryl, a C1-C10 carbonyl group, or a C1-C10 amine group;
- L is a linker;
- x is 1 to 10;
- and
- y is 5 to 1000, wherein the iron oxide oleic acid nanoparticle contains 4-10% Fe(II) ions relative to the total iron ions.
6 more elements
Dependencies are inferred from the claim text.