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US 12,268,678 B2Granted
Formulations of hydroxypyridonate actinide/lanthanide decorporation agents
AssigneeThe Regents of the University of California
InventorsRebecca J. Abergel, Taylor A. Choi, Kenneth N. Raymond, David K. Shuh
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Abstract
Provided herein are pharmaceutical formulations comprising a 1,2-HOPO chelating agent and/or a 3,2-HOPO chelating agent.
Claims20
A method for treating a subject for a heavy metal exposure, the method comprising:
- administering to the subject having an excess amount of heavy metal a therapeutically effective amount of a pharmaceutical composition comprising:
- a 1,2-HOPO chelating agent in an amount from about 100 mg to about 1500 mg;
- and
- sodium oleate,
- decorporating, clearing, and/or reducing the excess amount of heavy metal from the subject.
2 more elements
Dependencies are inferred from the claim text.