Monitoring of patients for sepsis based on radioisotope level
OwnerRoy Pinchotinventor
Life of this patent
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Abstract
A method, system, and computer program product for monitoring sepsis in a subject. A device may monitor expired air from the subject who has been administered a bicarbonate salt comprising a carbon-13 isotope. The device may measure a ratio of carbon dioxide comprising the carbon-13 isotope (13CO2) to carbon dioxide comprising a carbon-12 isotope (12CO2) in the monitored expired air and may determine a level of sepsis in the subject based on the ratio, where a lower ratio of 13CO2 to 12CO2 indicates an increased level of sepsis. The device may display an indication of the level of sepsis in the subject.
Claims17
A method of monitoring sepsis in a subject, the method comprising:
- monitoring expired air from the subject, wherein the subject has been administered a bicarbonate salt comprising a carbon-13 isotope;
- measuring a ratio of carbon dioxide comprising the carbon-13 isotope (13CO2) to carbon dioxide comprising a carbon-12 isotope (12CO2) in the monitored expired air, wherein the ratio correlates to a bloodstream level of lactic acid in the subject;
- determining a level of sepsis in the subject based on the ratio, wherein a lower ratio of 13CO2 to 12CO2 indicates an increased level of sepsis;
- and
- displaying an indication of the level of sepsis in the subject.
A device, the device comprising:
- a respiratory monitor configured to monitor expired air from a subject, wherein the subject has been administered a bicarbonate salt comprising a carbon-13 isotope;
- a processor configured to:
- measure a ratio of carbon dioxide comprising the carbon-13 isotope (13CO2) to a carbon dioxide comprising a carbon-12 isotope (12CO2) in the monitored expired air, wherein the ratio correlates to a bloodstream level of lactic acid in the subject;
- and
- determine a level of sepsis in the subject based on the ratio, wherein a lower ratio of 13CO2 to 12CO2 indicates an increased level of sepsis;
- and
- a display configured to display an indication of the level of sepsis in the subject.
A non-transitory computer program product for monitoring sepsis in a subject, the computer program product comprising:
- a computer-readable storage medium having program instructions embodied therewith, the program instructions executable by a computer to cause the computer to perform a method, comprising:
- receiving a carbon-13 isotope (13CO2) measurement and a carbon-12 isotope (12CO2) measurement in expired air from a subject, wherein the subject has been administered a bicarbonate salt comprising the carbon-13 isotope;
- determining a ratio of 13CO2 to 12CO2 based on the 13CO2 measurement and the 12CO2 measurement, wherein the ratio correlates to a bloodstream level of lactic acid in the subject;
- determining a level of sepsis in the subject based on the ratio, wherein a lower ratio of 13CO2 to 12CO2 indicates an increased level of sepsis;
- and
- displaying an indication of the level of sepsis in the subject.
Dependencies are inferred from the claim text.