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US 12,264,192 B2Granted
Modified collagen, methods of manufacture thereof
AssigneeJellagen Pty Ltd
InventorAndrew Mearns Spragg
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Abstract
The present invention provides a method of producing a modified collagen, including the steps of: providing a collagen comprising a S—S bond; introducing a —SH group in said collagen comprising a S—S bond by reduction of the S—S bond to provide a collagen thiol comprising a —SH group; and nitrosating the —SH group of the collagen thiol to provide a modified collagen, said modified collagen comprising S-nitroso groups.
Claims13
A method of producing a modified collagen, comprising at least the steps of:
- providing a collagen comprising a S—S bond;
- introducing a —SH group in said collagen comprising a S—S bond by reduction of the S—S bond to provide a collagen thiol comprising a —SH group;
- nitrosating the —SH group of the collagen thiol to provide a modified collagen, said modified collagen comprising S-nitroso groups.
Dependencies are inferred from the claim text.