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US 12,264,188 B2Granted
Relaxin-2 fusion proteins
AssigneeTectonic Operating Company, Inc.
InventorsJohn Diener, Ryan Knihtila, Franz Gruswitz
Life of this patent
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Abstract
Relaxin-2 fusion protein analogs with enhanced in vivo half-life and methods for making the same are described. Also described are methods of treating relaxin-2-associated disorders or diseases using the relaxin-2 fusion protein analogs.
Claims21
A fusion protein comprising, from N-terminus to C-terminus:
- a first peptide comprising the amino acid sequence set forth in SEQ ID NO:
- 1;
- a first linker peptide comprising the amino acid sequence set forth in SEQ ID NO:
- 21;
- and
- a second peptide comprising the amino acid sequence set forth in SEQ ID NO:
- 8.
4 more elements
Dependencies are inferred from the claim text.