Methods for treating or preventing obesity and body weight management
AssigneeBrillian Pharma Inc.
InventorsNuo Wang, Shaohui Lin, Xuening Hu
Life of this patent
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Abstract
This disclosure provides a method of administrating to a subject a two-portion solution system in a specific ingesting order to yield a water-insoluble cross-linked hydrogel mass in the stomach. The volume of the formed water-insoluble cross-linked hydrogel mass is at least 50% v/v of the total volume of the two-portion solution system. The method is useful for preventing and treating overweight and obesity.
Claims48
A method for or treatment of obesity or overweight, comprising a step-wise administration of a two-portion solution system to a subject suffering from obesity or overweight, wherein the two-portion solution system comprises a first solution and a second solution and the step-wise administration comprises:
- (i) administrating a unit dosage of the first solution comprising a cross-linker for crosslinking a hydrogel;
- and
- (ii) administrating a unit dosage of the second solution comprising a cross-linkable hydrogel polymer after the administration of the first solution,
- wherein the two-portion solution system forms a cross-linked hydrogel mass that is water-insoluble and has a volume of equal to or greater than 50% (v/v) of the total volume of the two-portion solution system.
Dependencies are inferred from the claim text.