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US 12,258,610 B2Granted
Production of chemicals from renewable sources
AssigneeZymochem, Inc.
InventorsHarshal Chokhawala, Jonathan Kuchenreuther, Jorge-Alonso Gutierrez, Yi-Shu Tai
Life of this patent
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Abstract
Among other things, the present disclosure provides biosynthesis polypeptides, methods, and non-naturally occurring microbial organisms for preparing various compounds such as 1,5-pentanediol, adipic acid, 1,6-hexanediol, 6-hydroxy hexanoic acid, and 2-keto carboxylic acids.
Claims14
A method, comprising:
- contacting pyruvate and HO—CH2—CH2—CHO (3-hydroxy propanal) with a polypeptide having the sequence of SEQ ID NO:
- 24 so that HO—CH2—CH2—CH═CH—C(O)—COOH (6-hydroxy-2-oxo-3-hexenoic acid) or a salt thereof is produced.
Dependencies are inferred from the claim text.