Recombinant vaccine against Marek's disease and Newcastle disease
AssigneeThe United States of America as represented by the Secretary of Agriculture
InventorsQingzhong Yu, Stephen J. Spatz, John R. Dunn
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Abstract
Provided herein are immunogenic compositions containing recombinant viruses capable of inducing protection in poultry against both Marek's disease virus (MDV) and Newcastle disease virus (NDV). Such viruses incorporate nucleic acids for expressing at least one MDV antigen, such as glycoprotein B, and antigenic portions thereof, in a recombinant NDV genome.
Claims10
A recombinant Newcastle disease virus (NDV), comprising a synthetic polypeptide having an amino acid sequence at least 95% identical to SEQ ID NO:2, and wherein the genome of the recombinant NDV is at least 95% identical to SEQ ID NO:
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A method of eliciting an immune response against Marek's disease virus (MDV) and Newcastle disease virus (NDV) in a subject, comprising administering to the subject a composition comprising a recombinant NDV expressing a synthetic polypeptide having an amino acid sequence at least 95% identical to SEQ ID NO:2, and wherein the genome of the recombinant NDV is at least 95% identical to SEQ ID NO:
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Dependencies are inferred from the claim text.